A 36-year-old man developed two eschars (localized skin lesions) after visiting a rural field in Manzini, Swaziland. He has general weakness, myalgia, night sweats and sore throat. He reports having no rash…
A previously healthy 35-year-old male presents with sudden onset of fever, fatigue, myalgia, and headache. He reports recent travel to an Ebola-endemic region in West Africa. The patient presented with signs…
Eva is a 50-year-old Caucasian woman who presents to the clinic with complaints of hand and feet swelling to the point of visible deformities. Her joint pain wakes her up several times during the night and she has morning stiffness for several hours.
Epigenetics Research in Systems Immunology: Concepts, Technologies and Future Concept of the Systems Immunology The conventional approach in immunology research has been ‘hypotheses’ driven, in which the Immunologist performs experiments, generates a set of observations and then develops a ‘mechanistic’ understanding at the end of the study. In contrast to this conventional paradigm, systems biology Read More
04 May 2022
Saithong, et al., have hypothesized now that severe COVID-19 causes leaky gut and gut translocation of pathogenic cell wall components enhancing the formation of NETs and sepsis severity…
Norberto, a 23-year old white male in his third relapse of a B cell acute lymphoblastic leukemia (B-ALL) has been treated with an infusion of autologous CD19 Chimeric Antigen Receptor (CAR) T cells (CAR-T cells). Ten days later, he felt severe discomfort in the middle of the night…
Immuno-Algeria Student Presentations Student Presentations – Week 1 Razika Zeghi-Bouteldja – Proteomic characterization of antigens involved in allergic reaction during cystic echiococcosis Sadjia Lahiani – Identification of immunodominant epitope residues of Der p 5 Allergen from Dermatophagoides pteronyssinus by alanine scanning strategy Mohamed Anis Boussahel – Agreement between Skin prick tests and specific IgE Read More
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Tumours are organ-like structures composed of different cell types whose interactions are required to promote their maintenance, growth and metastasis. Increasing evidence indicates that the tumour microenvironment (TME) can dictate aberrant cellular function and play a critical role in the subsequent development of more advanced and refractory malignancies. TME is constituted of cancer-associated fibroblast (CAFs), Read More
What Is Inflammation? Inflammation (Latin, inflammatio, to set on fire) is the complex biological response of vascular tissues to injury or harmful stimuli, such as those caused by pathogens, damaged cells, or irritants. In general, the following events occur during an inflammatory response: Vascular changes: blood flow increases and fluid and plasma proteins leak into Read More