Asia


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Immunopaedia Ambassadors – Asia

Our Ambassadors from across the Asian continent.


What is your name?
Diwakar Rathour

What is your current position?
Senior Research Fellow

Which institute and country do you work in?
National Institute of Immunology India

What is your home country?
India (Firozabad, U.P.)

What are your research interests?
Infection Biology, Basic immunology

Tell us about yourself and your research interests:
I am currently working in the National Institute of Immunology India as Senior Research Fellow. I did my master from St.Johns College Agra and M.phil from School of life science, Khandari Campus, DR.Bhimrao Ambedakar University Agra. Since 3 Year, I am interesting in the field of immunology. My early carrier work done in the National JALMA institute of leprosy and Other Mycobacterium disease Agra. This involved the Study of TCR mediated Proximal and Distal T cell signalling events in the Blood and peripheral fluid of TB pleurisy patients. We examined the level of Intracellular Calcium, ZAP70, Erk1/2, P-38 that is essential in the T cell proliferation and regulation. I am currently studying to determine whether CD40 signaling contributes to the maintenance of the memory and plasma cells.

What are your online profiles?
LinkedIn –Diwakar Rathour
Researchgate –Diwakar Rathour

Immunology Keywords:
T cell, B cell, Cell Signaling


What is your name?
Dimpu Gogoi

What is your current position?
Scientist

Which institute and country do you work in?
Indian Council of Medical Research (ICMR)- National Institute for Research in Reproductive Health (NIRRH), Mumbai, India

What is your home country?
India

What are your research interests?
Immunology of chronic diseases, Immunotolerance and T cell biology

Tell us about yourself and your research interests:
I am working as a Scientist at ICMR-NIRRH, Mumbai, India. I started my journey in the field of immunology after enrolling for a doctorate degree at ACTREC-HBNI, India, which resulted in elucidating the importance of notch signal in regulating effector functions of γδ T cells. During my overseas postdoctoral fellowship at Institut Pasteur, France, I studied the involvement of T cells in conferring protection against Plasmodium mediated neuropathogenesis during chronic Toxoplasma gondii infection. I received INSPIRE Faculty award to work as an independent investigator to examine the role of exhaustion markers in γδ T cells and its possible involvement in regulating the severity of chronic pathogenic infections such as P. vivax-malaria and hepatitis B. Currently, I am interested in understanding the fine tuning of T cell responses that keep pathogens in check without causing any significant damage to self in chronic infectious diseases.

What are your online profiles?
LinkedIn – Dimpu Gogoi
Researchgate – Dimpu Gogoi

Immunology Keywords:
T cells, Immune exhaustion and Chronic diseases


What is your name?
Babita Balakrishnan

What is your current position?
Reviewer

Which institute and country do you work in?
Previous Affiliation: Indian Institute of Science (IISc), Bengaluru, India

What is your home country?
India

What are your research interests?
Osteoimmunology, Transplantation Immunology

Tell us about yourself and your research interests:
My primary research area of interest is Immunology. Both my doctoral and post doctoral experiences have helped me widen my understanding of the immune system. As a researcher, I strongly believe in taking research from bench-to-bedside. My post doctoral work from IISc, Bengaluru involved the investigation of role of Glycodelin, a natural immunosuppressor, in averting graft versus host reaction. We developed an allograft nude mouse model for this study and the Cytotoxic T Lymphocytes (CTLs) mediated killing of donor graft was clearly evident in this model. The transplanted graft survived successfully as glycodelin was able to downregulate the factors which regulate the cytotoxicity of CTLs and thus helped in the management of graft rejection.

My doctoral work from D. G. Ruparel College and ACTREC, Mumbai highlighted the potential of marine mollusc as an anti-osteoporotic agent and also identified its role in regulating lymphocyte-bone interaction. The extract was also able to control the increased T cell expression and secretion of pro-inflammatory cytokines followed by ovariectomy. This work was awarded with Young Scientist Award at the 9th International Marine Biotechnology Conference, China and also bagged best poster award at Immunocon, NIMHANS, Bengaluru.

As a lecturer, I have conducted lectures and practicals in immunology for undergraduates and postgraduates. As a researcher, I would like to be actively involved in studying and unravelling the intricacies of the immune system and make myself adept in Immunology.

What are your online profiles?
LinkedIn – Babita Balakrishnan
Researchgate – Babita Balakrishnan

Immunology Keywords:
Transplantion Immunology, Osteoimmunology, immunosuppression


What is your name?
Rushikesh Sudam Patil

What is your current position?
Post-Doctoral Fellow “INSPIRE Faculty” supported by Department of Science and Technology, Govt of India

Which institute and country do you work in?
Department of Immunology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC)- Tata Memorial Centre, Kharghar, Navi Mumbai, India

What is your home country?
India

What are your research interests?
Gamma delta T cells, T cell metabolism and Cancer

Tell us about yourself and your research interests:
I completed my PhD in 2016 under the mentorship of Prof S.V. Chiplunkar from ACTREC-Tata Memorial Centre, Navi Mumbai. The research work focused on understanding the immune dysfunctions in pathogenesis of gallbladder cancer patients in India. Highlight of the study was to show that the IL17 secreting γδ-T lymphocytes (Tγδ17) induce angiogenesis and are associated with poor survival of Gallbladder cancer patients. This work received “Dr. G P Talwar young scientist award” from Indian Immunology Society. I then commenced a post-doctoral fellowship to investigate the role of exhaustion of T lymphocytes infiltrating the tumor environment of colon cancer patients, a project headed by Dr. S.V. Chiplunkar, in collaboration with ‘Bristol Meyer Squibb’, Bangalore. Recently I received an “INSPIRE Faculty award” to work at ACTREC-Tata Memorial Centre, Navi Mumbai. This is a competitive research grant given by Department of Science and Technology, Govt. of India to young investigators to pursue independent research. This grant was awarded for a project ‘Understanding the metabolic pathways regulating the functions of γδ-T cells in cancer’ which was selected after a stringent review process.

I am keen to investigate the metabolic regulation of T cells in inflammatory environment. ‘How antigenic stimulation rewires the metabolic need of gamma delta T cells and vice versa in tumor environment’ and ‘does the alterations in the metabolic preferences contribute to T cell exhaustion in tumor environment’ are the questions I am presently perusing. I am actively involved in teaching basic immunology to undergraduate students and I participate in the Immunology hands-on training workshops organised by ‘Mumbai Immunology Group’.

What are your online profiles?
Researchgate: Rushikesh Patil

Immunology Keywords:
Inflammation, T cells, Metabolism, immune exhaustion

 

 

 
 
 
 
 
 
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