MHC immune responses

In the 1960s, studies done by Baruj Benacerraf and colleagues (Levine et al. J Exp Med 118:953, 1963) and Hugh McDevitt and coworkers (J Exp Med 126:969, 1967), amongst others, revealed that the MHC genes controlled specific immune responses through what they called Immune Response genes (Ir genes).

International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University