Lymphocyte Differentiation

F. A P. Miller in a series of classical experiments demonstrated that neonatally thymectomized mice are lymphopenic and immunodeficient and proposed that the thymus is the lymphoid organ where small immunocompetent lymphocytes are differentiated.

Miller, Lancet 278:748-749, 1961; Miller, Nature 195: 138-1319, 1962; Miller, Proc Roy Soc London B 16:415-428, 1962

International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University