Invariant Chain

Jones et al., (Mol Immunol 16:51, 1979) reported the existence of an invariant chain (Ii) that binds the α and β class II chains in the endoplasmic reticulum (ER), before the trimer moves to the Golgi apparatus.

International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University