B cells and T cells

Angelo M DiGeorge described the association of thymic aplasia, hypoparathyroidism and infection (DiGeorge´s syndrome). In the same paper Max D Cooper et al., proposed the existence of two types of immune responses: one mediated by lymphocytes generated in the Bursa of Fabricius in birds (B cells) and responsible for the production of antibodies, and the other mediated by lymphocytes differentiated in the thymus (T cells) and responsible for the cell-mediated immune responses

Cooper et al. J Pediatrics 67: 907-908, 1965