Antigen Recognition


In 1977, Els Goulmy et al. (Nature 266:544, 1977) demonstrated that antigen recognition by CD8 T cells was restricted by class I molecules, while Bergholtz and Thorsby (Scand J Immunol 6:779, 1977) showed that class II molecules restrict antigen recognition by CD4 T cells.


 
     
 
 
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