Antigen Recognition

In 1977, Els Goulmy et al. (Nature 266:544, 1977) demonstrated that antigen recognition by CD8 T cells was restricted by class I molecules, while Bergholtz and Thorsby (Scand J Immunol 6:779, 1977) showed that class II molecules restrict antigen recognition by CD4 T cells.

International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University