Anti-leukocyte antibodies

Rose Payne in the US (J Clin Invest 37:1756, 1958) and Jon van Rood in the Netherlands (Nature 151:1735, 1958) working independently reported the presence of anti-leukocyte antibodies in the sera of pregnant women. This set the momentum for the availability of mono or oligospecific HLA antisera to determine HLA antigens in an individual.

International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University