Mitotic spindle

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The molecular ‘motor’ that will segregate chromatids to daughter cells during mitosis.It is composed of polar centrosomes from which microtubules extend towards the equatorial chromatid plate, forming a spindle-shaped structure.



Walczak CE and Heald R. Mechanisms of mitotic spindle assembly and function.Int Rev Cytol.2008; 265.

O’Connell CB and Khodjakov AL. Cooperative mechanisms of mitotic spindle formation.J Cell Sci 2007; 120.

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International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University