Found on Cytotoxic T lymphocytes (CTL) and natural killer cells. The CD8 receptor on CTL binds to HLA class I and the interaction causes CD8 T cell activation. These cells are able to identify and kill cells infected primarily with viruses, but also many bacterial infections.

« Back to Glossary Index
International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University