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METABOLISM: A GUIDING FORCE FOR IMMMUNITY Metabolism in simple terms refers to the cellular reactions that lead to energy generation from food such as breaking down proteins into amino acids, carbohydrates into simple sugars such as glucose, fats into fatty acids, etc. It is organised into different metabolic pathways to maximise the capture of energy Read More

Targeting the Tumour Microenvironment Tumor microenvironment (TME) is a complex, dynamic battlefield for both immune cells and tumour cells. TME is composed of tumour cells, various cytokines, chemokines, proteases, many enzymes, macrovesicles, and other secreted molecules. TME mainly consists of cancer-associated fibroblast (CAFs), endothelial cells, immune cells (like tumour associated macrophages (TAMs)), myeloid derived suppressor Read More

Regulatory B cells (Bregs) are immunosuppressive cells that contribute to the reduction of excessive inflammatory responses. Researchers have demonstrated that interaction between the gut microbiota and the innate immune system in the gut-associated lymphoid tissue (GALT) promotes the differentiation of immature B cells into B-regs. Mice depleted of endogenous bacteria following administration of broad-spectrum antibiotics Read More

9th June

In a recent IUIS-Immunopaedia-Frontiers in Immunology webinar, Claudia Mauri discussed how microbial products induce B-regs and their relevance for arthritis pathology. Murine models of arthritis have demonstrated that pathology is associated…

Our April Ambassador of the month is Theodorus van den Broek,  Senior Postdoctoral Research Fellow at the Center for Translational Immunology (CTI) UMCU The Netherlands. Theo has contributed to Immunopeadie by writing multiple research summaries. He also recently took part in the Nature Webcast Series on How to master peer review.

July 2020

Dr Ranchod completed her BSc at the University of the Witwatersrand, and pursued both completed her post-graduate training at University of Pretoria. Her research focus is on TB immunology. She initially began her research career focusing on antibodies and, has now moved to the field of TB-host immuno-metabolism.

19th November

Day 4 of the Immuno-Jaipur included talks from renowned Professors Shubhada Chiplunka, Sunil Arora, Hannes Stockinger, Abul Abbas and Oliver Boyer. In think article we shall highlights information relayed by Profs Chuplunka, Arora and Abbas. Prof. Shubhada Chiplunkar, ACTREC-Tata Memorial Centre, addressed the audience on the…

The immune response to cancer is best viewed as a specialized case of immunity in which the malignant cell has adapted and learned how to persist. The immunological surveillance theory was originally put forth independently by Burnet and Thomas, who suggested that the immune system continually surveyed the body for the presence of malignant cells, Read More

The immune response to cancer is best viewed as a specialised case of immunity in which the malignant cell has adapted and learned how to persist. The immunological surveillance theory was originally put forth independently by Burnet and Thomas, who suggested that the immune system continually surveyed the body for the presence of malignant cells, Read More

November 2017

Our November Immunologist of the Month is Mohlopheni Jackson Marakalala, Senior Lecturer at the University of Cape Town and Visiting Scientist at the Harvard T.H Chan School of Public Health. Mohlopheni obtained his PhD…