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Tumour Microenvironment

Tumours are organ-like structures composed of different cell types whose interactions are required to promote their maintenance, growth and metastasis. Increasing evidence indicates that the tumour microenvironment (TME) can dictate aberrant cellular function and play a critical role in the subsequent development of more advanced and refractory malignancies. TME is constituted of cancer-associated fibroblast (CAFs), Read More

Inflammation and autoinflammation

What Is Inflammation? Inflammation (Latin, inflammatio, to set on fire) is the complex biological response of vascular tissues to injury or harmful stimuli, such as those caused by pathogens, damaged cells, or irritants. In general, the following events occur during an inflammatory response: Vascular changes: blood flow increases and fluid and plasma proteins leak into Read More

Inflammation and autoinflammation

What Is Inflammation? Inflammation (Latin, inflammatio, to set on fire) is the complex biological response of vascular tissues to injury or harmful stimuli, such as those caused by pathogens, damaged cells, or irritants. In general, the following events occur during an inflammatory response: (1) vascular changes: blood flow increases and fluid and plasma proteins leak Read More

Tumour Microenvironment

Tumours are organ-like structures composed of different cell types whose interactions are required to promote their maintenance, growth and metastasis. Increasing evidence indicates that the tumour microenvironment (TME) can dictate aberrant cellular function and play a critical role in the subsequent development of more advanced and refractory malignancies. TME is constituted of cancer-associated fibroblast (CAFs), Read More

5. Tumor Microenvironment

Tumors are organ-like structures composed of different cell types whose interactions are required to promote their maintenance, growth and metastasis. Increasing evidence indicates that the tumor microenvironment (TME) can dictate aberrant cellular function and play a critical role in the subsequent development of more advanced and refractory malignancies. TME is constituted of cancer-associated fibroblast (CAFs), Read More

6. Inflammation and autoinflammation

What Is Inflammation? Inflammation (Latin, inflammatio, to set on fire) is the complex biological response of vascular tissues to injury or harmful stimuli, such as those caused by pathogens, damaged cells, or irritants. In general, the following events occur during an inflammatory response: (1) vascular changes: blood flow increases and fluid and plasma proteins leak Read More

8. Inflammation and autoinflammation

What Is Inflammation? Inflammation (Latin, inflammatio, to set on fire) is the complex biological response of vascular tissues to injury or harmful stimuli, such as those caused by pathogens, damaged cells, or irritants. In general, the following events occur during an inflammatory response: (1) vascular changes: blood flow increases and fluid and plasma proteins leak Read More

A case of acute fever, rash and vomiting

A 31 year old caucasian male presented to the HIV clinic complaining of recent onset of fever, vomiting, joint pain, muscle aches, sore throat and a fine red rash on his face and arms. All symptoms had worsened since they first started 2 days ago and seemed to be aggravated shortly…

 
 
 
 
 
 
International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University