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Tuberculosis Protracted or chronic bacterial infections are often caused by organisms that have an intracellular phase; this requires that they are adept at the penetration, evasion, and exploitation of the host immune response. The classic example of a chronic bacterial infection is seen with Mycobacterium tuberculosis, the causative organism of tuberculosis (TB), a major public health Read More

09 September 2024

An immunology throwback – This article delves into the roles of TNF-α and IL-17 in disease progression, focusing on their mechanisms of action, the synergistic effects they produce when acting together, and their potential as therapeutic targets…

Eva is a 50-year-old Caucasian woman who presents to the clinic with complaints of hand and feet swelling to the point of visible deformities. Her joint pain wakes her up several times during the night and she has morning stiffness for several hours.

Tuberculosis Protracted or chronic bacterial infections are often caused by organisms that have an intracellular phase; this requires that they are adept at the penetration, evasion, and exploitation of the host immune response. The classic example of a chronic bacterial infection is seen with Mycobacterium tuberculosis, the causative organism of tuberculosis (TB), a major public health Read More

The immune system evolves multiple mechanisms for controlling self-reactivity, and defects in one or more of these mechanisms can lead to breakdown of central or peripheral tolerance. Under certain circumstances this system can be misdirected towards self antigens Accordingly, aberrant responses against self are implicated in >80 inflammatory disorders, collectively defined as autoimmune diseases. Among Read More

Tuberculosis Protracted or chronic bacterial infections are often caused by organisms that have an intracellular phase; this requires that they are adept at the penetration, evasion, and exploitation of the host immune response. The classic example of a chronic bacterial infection is seen with Mycobacterium tuberculosis, the causative organism of tuberculosis (TB), a major public health Read More

Immuno-Algeria Student Presentations   Student Presentations – Week 2 Lorraine Tsitsi Pfavayi – Characterising serological reactivity to fungal antigens in Zimbabwean children Arezki Samer – Ameliorative effect of probiotic supernatant on indomethacin-induced small intestinal injury in mouse models of inflammatory bowel diseases: The experimental enteropathy. Khaoula Attia – Hyper IgE Syndrome: Clinical and biological features Read More

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Protracted or chronic bacterial infections are often caused by organisms that have an intracellular phase; this requires that they are adept at the penetration, evasion, and exploitation of the host immune response. The classic example of a chronic bacterial infection is seen with Mycobacterium tuberculosis (M.tb), the causative organism of tuberculosis. These bacteria invade the Read More

The human immune system is a complex network of specialised cells and organs that protects the body from infections. At the core of the immune system is the ability to recognise the difference between self and non-self. Autoimmune diseases arise from an overactive and misguided immune response of the body against substances and tissues normally Read More