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23 July 2024

A new study aimed to elucidate the complex immune responses involved in COVID-19 to identify biomarkers that predict different clinical outcomes…

27 May 2024

In a recent study, researchers examined and described the macrophage–neutrophil axis in Mtb infection, assessing neutrophil function…

Eva is a 50-year-old Caucasian woman who presents to the clinic with complaints of hand and feet swelling to the point of visible deformities. Her joint pain wakes her up several times during the night and she has morning stiffness for several hours.

B cells: function and repertoire Respond to antigens and differentiate into plasmablasts and plasma cells Plasmablasts and plasma cells secrete antibodies Protection from infectious disease Immobilization – flagellae of motile bacteria Cytolysis – complement fixation Opsonization – phagocytosis via Fc receptors Activated B cells can secrete cytokines such as pro-inflammatory IL-6 and TNF-a Take up Read More

June 2024 Alejandra Urioste is a biochemist and a pharmacist who graduated from the University of Buenos Aires (Universidad de Buenos Aires, Facultad de Farmacia y Bioquimica), Argentina. During her residency in Clinical Immunology and her PhD project, she worked mostly on the immune response against HIV and HCV. Alejandra is currently at the Histocompatibility Read More

Immunological systems function as soldiers to resist illness, but under some circumstances, the soldiers are reprogrammed to limit immunological response. These specific circumstances appear in cancer and illness.  These reprogrammed immune cells are one of the most exciting areas of study and targeting them can be extremely useful to patients.   These immunosuppressive cells are broadly Read More

Introduction Immunological tolerance describes a diverse range of host processes that prevent potentially harmful immune responses within that host (1). A fundamental property of the immune system is its ability to mediate self-defense with minimal collateral damage to the host. The system uses several different mechanisms to achieve this goal, which is collectively referred to Read More

22 January 2024

In a recent study, researchers identified a method to block IL-6 signals to treat cytokine release syndrome, with minimised side effects…

01 September 2023

In a recent study, researchers have uncovered how severe cases of COVID-19 can lead to enduring alterations in the innate immune system…