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Redirecting Cytotoxicity

Cell-based Cancer Therapies Cytotoxicity is a property of some immune cells to induce lysis of other cells that can be detected as non-functional or transformed. In the recent years, redirecting cytotoxicity in cancer has been the base of cell-based cancer therapies that involve the use of living cells to treat cancer. There are several types Read More

Student Presentations – Week 1

Immuno-Algeria Student Presentations   Student Presentations – Week 1 Razika Zeghi-Bouteldja – Proteomic characterization of antigens involved in allergic reaction during cystic echiococcosis Sadjia Lahiani – Identification of immunodominant epitope residues of Der p 5 Allergen from Dermatophagoides pteronyssinus by alanine scanning strategy Mohamed Anis Boussahel – Agreement between Skin prick tests and specific IgE Read More

Immuno-Algeria Programme

Download the Programme – Immuno-Algeria Programme.xlsx  

Immuno-Jaipur Highlight: Part 2 of Day 3

15th November

In addition to talks by Prof Abbas, Day 3 of Immuno-Jaipur included talks on autoimmunity and chronic inflammation. Prof. Bernhard Fleisher gave a talk on autoimmunity in the central nervous system where he discussed various autoimmune diseases such as Myasthenia Gravis, Encephalitis, Multiple sclerosis. Myasthenia gravis is an autoimmune disease…

Breaking Tolerance: Autoimmunity & Dysregulation

Introduction The immune system’s three basic functions are Defence, Surveillance and Homeostasis Elaborate and redundant tolerance mechanisms are in effect both during maturation and later in the lymphocyte life-cycle, leading to clonal deletion or anergy Anergy can be reversed to allow recruitment of autoreactive clones to maximise receptor diversity (e.g. during infection) Autoimmunity (Table 1) Read More

Autoimmunity & Dysregulation

Introduction The immune system’s three basic functions are Defence, Surveillance and Homeostasis Elaborate and redundant tolerance mechanisms are in effect both during maturation and later in the lymphocyte life-cycle, leading to clonal deletion or anergy Anergy can be reversed to allow recruitment of autoreactive clones to maximise receptor diversity (e.g. during infection) Autoimmunity (Table 1) Read More

Breaking Tolerance: Autoimmunity & Dysregulation

Introduction The immune system’s three basic functions are Defence, Surveillance and Homeostasis Elaborate and redundant tolerance mechanisms are in effect both during maturation and later in the lymphocyte life-cycle, leading to clonal deletion or anergy Anergy can be reversed to allow recruitment of autoreactive clones to maximise receptor diversity (e.g. during infection) Autoimmunity [Table 1] Read More

My eyes cross at twilight

A 25 years-old, teacher, complains of double vision. She finds it difficult to talk after prolonged speaking. She is pregnant.Episodes of double vision began 6 weeks ago. Elsa’s husband reported fluctuating droopy eyelids in the morning and evening, which started 4 weeks ago.

6. Tolerance and Autoimmunity

Introduction Erlich put forward the term ‘horror autotoxicus’ to refer to the body’s aversion to immunological self destruction, and postulated that mechanisms must prevent reaction against self Healthy individuals have a smouldering autoimmune response that can escape control (a system of many checks and balances) to cause autoimmune disorders A major area of interest is Read More

4. Breaking Tolerance: Autoimmunity & Dysregulation

Introduction The immune system’s three basic functions are Defence, Surveillance and Homeostasis Elaborate and redundant tolerance mechanisms are in effect both during maturation and later in the lymphocyte life-cycle, leading to clonal deletion or anergy Anergy can be reversed to allow recruitment of autoreactive clones to maximise receptor diversity (e.g. during infection) Autoimmunity (Table 1) Read More

 
 
 
 
 
 
International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University