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cAMP and EPAC are Key Players in the Regulation of the Signal Transduction Pathway Involved in the a-Hemolysin Autophagic Response
Staphylococcus aureus can infect various types of non-professional phagocytic cells and after internalization is able to escape the phagolysosomal compartment towards the cytoplasm, where it actively replicates.[more]
Evaluation of PIMA point-of-care CD4 testing in a large UK HIV service
CD4 cell monitoring is an essential component of routine HIV care and is used to monitor disease progression as well as guiding decisions about the use of antiretroviral therapy and prophylactic treatment for infections.[more]
The epitope and neutralization mechanism of AVFluIgG01, a broad-reactive human monoclonal antibody against H5N1 influenza virus
Highly pathogenic avian influenza (HPAI) H5N1 viruses continue to spread among poultry and have frequently broken the species barrier and transmitted to humans.[more]
Default in plasma and intestinal IgA responses during acute infection by Simian Immunodeficiency Virus
The gastrointestinal tract is a privileged site for both HIV-1/SIV replication and extensive CD4+ T-cell depletion at all stages of the pathogenic infection[more]
Activated iNKT Cells Promote Memory CD8+ T Cell Differentiation during Viral Infection
Recent studies have proposed that the prototypical lipid ligand for invariant NKT cells (iNKT cells), a-galactosylceramide (a-GalCer), is an effective adjuvant in vaccination against a range of immune challenges.[more]
EBV immunoevasins protect newly infected B Cells from immune recognition and elimination
Epstein-Barr virus (EBV) results in a lifelong persistence which is mainly owed to the virus' pronounced abilities to evade immune responses of its human host.[more]
Pregnancy and infant outcomes among HIV-Infected women taking long-term ART with and without Tenofovir in the DART trial
In sub-Saharan Africa alone, 12 million women are HIV-positive. [more]
