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Anthrax Toxin induces Macrophage Death but leads to Inflammasome Activation via ATP Leakage
This week's issue of the journal Immunity reports on the findings of Scientists from UCLA and Skaggs School of Pharmacy and Pharmaceutical Sciences who have uncovered how the immune system launches its survival response to Bacillus anthracis.[more]
Acute Hepatitis A Virus Infection is associated with a Limited type I Interferon Response and Persistence of Intrahepatic viral RNA
A surprising finding in a study comparing hepatitis C virus (HCV) with hepatitis A virus (HAV) infections in chimpanzees has shed new light on the nature of the body's immune response to these viruses.[more]
HIV/SIV Infection Primes Monocytes and Dendritic Cells for Apoptosis
Antigen-presenting cells (APCs) are critical for both innate and adaptive immunity.[more]
Duffy Negative Antigen no Longer a Barrier to Plasmodium Vivax
Recent reports of Plasmodium vivax infections, the most widely distributed species of human malaria, show that this parasite is evolving and adapting, becoming not only more aggressive but also more frequent in countries where it was not present in the past.[more]
MDA5 and TLR3 Initiate Pro-Inflammatory Signaling Pathways Leading to Rhinovirus-Induced Airways Inflammation and Hyperresponsiveness
Rhinovirus (RV), a single-stranded RNA picornavirus, is the most frequent cause of acute respiratory tract infection in humans and has emerged as the most frequent pathogen associated with exacerbations of asthma.[more]
“Rational Vaccine Design” for HIV should take into account the adaptive potential of Polyreactive Antibodies
The long-standing quest for the development of vaccines that confer protection against highly mutable viruses such as HIV, hepatitis C, and influenza has elicited numerous structural and functional studies on virus-neutralizing human antibodies. [more]
The Risk of Anaphylaxis in Percutaneous Treatment of Cystic Echinococcosis—A Systematic Literature Review
Percutaneous treatment (PT) emerged in the mid-1980s as an alternative to surgery for selected cases of abdominal cystic echinococcosis (CE).[more]

