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30.11.2010

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

Scientists at Gladstone Institute of Virology and Immunology have identified the mechanism by which CD4 T cells are depleted in HIV-infected hosts.[more]

Category: Breaking News

29.11.2010

The Origins of Autoimmunity-Causing T Cells

T cells play a major role in the immune system. Depending on which cytokines are present as a T cell matures, will depend on the type of T helper cell it develops into, each with their own distinct role in immunity.[more]

Category: Breaking News

26.11.2010

Most patients in darunavir monotherapy trial stay fully suppressed

The latest data from a European trial (MONET) using boosted darunavir (DRV/r) as the sole HIV drug has found no evidence of increased treatment failure or of viral loads increasing over time, even when viral loads below the usual limit of detectability were investigated with an ultrasensitive assay.[more]

Category: Breaking News

25.11.2010

Higher levels of Zidovudine resistant HIV in the colon compared to blood and other gastrointestinal compartments in HIV infection

It has been proposed that HIV-1 can "hide" from antiretroviral therapy in the gut, and drug-resistance may be compartmentalized.[more]

Category: Breaking News

24.11.2010

Combination of ARV drugs given to HIV negative people provides partial protection from HIV infections

Another breaking study this year shows that a combination of emtricitabineand te nofovir disoproxil fumarate (FTC­TDF), taken orally on a daily basis by men and transgender women who have sex with men, was found to provide partial protection from HIV infection.[more]

Category: Breaking News

23.11.2010

Nevirapine / rifampicin interaction linked to higher recurrence of TB in people on ART

Indian researchers at the Tuberculosis Research Centre in Chennai designed a randomised study to investigate the extent to which responses to HIV treatment and TB treatment are compromised by drug interactions. [more]

Category: Breaking News

22.11.2010

Dengue Virus Ensures Its Fusion in Late Endosomes Using Compartment-Specific Lipids

Dengue virus infection is a growing public health problem with up to 100 million cases annually, and no vaccine or effective therapies yet available.[more]

Category: Breaking News

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