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Switch to nevirapine can happen at any CD4 count
The European Medicines Agency has issued a revised “Summary of Product Characteristics” which permits people with suppressed viral load to switch to nevirapine.[more]
Rapid Molecular detection of Tuberculosis and Rifampin Resistance
Global control of tuberculosis is hampered by slow, low sensitivity diagnostic methods, particularly for the detection of drug-resistant forms and in patients infected with HIV. [more]
Kaposi sarcoma occurring at higher CD4 counts
A recent US Military Study reviewed over 5000 medical records between 1985 and 2008 and found that although rates of Kaposi sarcoma have fallen since effective antiretroviral therapy became available, the proportion of cases occurring at higher CD4 cell counts has increased[more]
How a normally defensive immune response can help HIV
Researchers have identified how a normal response to infection, one that usually serves to limit the amount of inflammation, actually contributes to disease progression and viral persistence in HIV-infected patients.[more]
Suppression of Cell-Mediated Immunity following Recognition of Phagosome-Confined Bacteria
This study examines Listeria monocytogenes a facultative intracellular pathogen capable of inducing a robust cell-mediated immune response to sub-lethal infection.[more]
Novel Sensing Mechanism Discovered in Dendritic Cells to Increase Immune Response to HIV
Dendritic cells, the immune cells found in skin, mucosa and lymph tissues, mediate the innate detection of pathogens and the activation of other immune cells involved in specific adaptive immunity.[more]
Truvada/Kaletra HIV PEP combination is safe and effective with a low rate of discontinuations
In Europe the recommended treatment for both occupational and non-occupational post-exposure prophylaxis (PEP) is two nucleoside reverse transcriptase inhibitors (NRTIs) and a ritonavir-boosted protease inhibitor.[more]

