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Discovering naturally processed antigenic determinants that confer protective T cell immunity
Understanding vaccine-mediated correlates of immunity is critical for the design of novel pathogen-free vaccines against diseases caused by complex pathogens such as HIV, malaria and TB.[more]
Peripheral B cell tolerance defects observed in patients with multiple sclerosis
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system caused by an autoimmune response in genetically susceptible individuals. [more]
IL-21 restricts virus-driven Treg cell expansion
T cell exhaustion represents a state of T cell dysfunction that is associated with viral infections and certain cancers.[more]
H7N9 and novel Coronavirus
The Center for Disease Control (CDC) has reported two new deadly virus’s the Coronavirus (NCoV) originating in the Middle East and the H7N9 virus originating in China. [more]
TRAIL+ T cells suppress GVHD and augment antitumor activity
Although allogeneic hematopoietic stem cell transplantation (allo-HSCT) has improved over the years, successful treatment remains limited by disease relapse and graft-versus-host-disease (GVHD)[more]
Immunohistochemical diagnosis of human alveolar echinococcosis with monoclonal antibody Em2G11
Echinococcosis is caused by the larval stages of the tapeworms Echinococcus multilocularis and Echinococcus granulosus.[more]
